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Véronique Calleja

London Research Institute

28

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1376

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Equivocal, explicit and emergent actions of PKC isoforms in cancer.

2020 Nature Reviews Cancer
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A Complex Interplay of Anionic Phospholipid Binding Regulates 3′-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation

2019 Scientific Reports
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PTEN-Mediated Leukemogenesis Bypasses Normal Requirement for PDK1 to Activate Downstream PI3K Pathway as Mechanism of Cancer Survival in A Lineage-Specific Manner

2018 Experimental Hematology
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A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

2016 Scientific Reports
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Endomembrane PtdIns(3,4,5)P3 activates the PI3K-Akt pathway.

2015 Journal of Cell Science
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Acute regulation of PDK1 by a complex interplay of molecular switches

2014 Biochemical Society Transactions
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The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies.

2013 Biochemistry
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Role of the C-terminal regulatory domain in the allosteric inhibition of PKB/Akt.

2012 Advances in biological regulation
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Protein Activation Dynamics in Cells and Tumor Micro Arrays Assessed by Time Resolved Förster Resonance Energy Transfer

2012 Methods in Enzymology
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A direct role for Met endocytosis in tumorigenesis

2011 Nature Cell Biology
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Citations (187)