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Julie E. Spooner

University of Hertfordshire

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Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams

2001 Bioorganic & Medicinal Chemistry Letters
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Corrigendum to “Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams”

2001 Bioorganic & Medicinal Chemistry Letters
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Corrigendum to “Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams”: [Bioorg. Med. Chem. Lett. 11 (2001) 243]

2001 Bioorganic & Medicinal Chemistry Letters
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A stereoselective synthesis via a 5-exo-trig cyclisation of trans-2-oxohexahydro-2H-furo[3,2-b]pyrroles (pyrrolidine-trans-lactones)—potent, novel elastase inhibitors

1998 Journal of The Chemical Society-perkin Transactions 1
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Synthesis of (+/-)-Oxohexahydrofuro[3,2-b]pyrroles (Pyrrolidine-trans-lactones) Using Acyl-Iminium Chemistry

1998 Synlett
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Syntheses of trans-5- Oxo-hexahydro-pyrrolo[3,2-b]pyrroles and trans-5-Oxo-hexahydro-furo[3,2-b]pyrroles (Pyrrolidine trans-Lactams and trans-Lactones): New Pharmacophores for Elastase Inhibition

1998 Journal of Medicinal Chemistry
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