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Dhaval K. Shah

University at Buffalo
State University of New York System

76

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1312

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Development and Application of a Single Cell-Level PK-PD Model for ADCs

2021
- Shufang Liu
- Dhaval K. Shah
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Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis.

2021 mAbs
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Heparan Sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE

2021 bioRxiv
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Two-pore physiologically based pharmacokinetic model validation using whole-body biodistribution of trastuzumab and different-size fragments in mice.

2021 Journal of Pharmacokinetics and Pharmacodynamics
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Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models

2021 Advanced Drug Delivery Reviews
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Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies

2021 bioRxiv
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A Two-Pore Physiologically Based Pharmacokinetic Model to Predict Subcutaneously Administered Different-Size Antibody/Antibody Fragments.

2021 Aaps Journal
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Antibody-drug conjugate and free geldanamycin combination therapy enhances anti-cancer efficacy.

2021 International Journal of Pharmaceutics
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Age-Related Changes in Pediatric Physiology: Quantitative Analysis of Organ Weights and Blood Flows : Age-Related Changes in Pediatric Physiology.

2021 Aaps Journal
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A population physiologically-based pharmacokinetic model to characterize antibody disposition in pediatrics and evaluation of the model using infliximab

2021 British Journal of Clinical Pharmacology
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