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J.E.H. Tattersall

Salisbury University

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Evaluation of the Influence of Three Newly Developed Bispyridinium Anti‐Nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice

2018 Basic & Clinical Pharmacology & Toxicology
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The efficacy of HI-6 DMS in a sustained infusion against percutaneous VX poisoning in the guinea-pig.

2017 Toxicology Letters
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Bioscavenger is effective as a delayed therapeutic intervention following percutaneous VX poisoning in the guinea-pig

2017 Toxicology Letters
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Efficacy of the antinicotinic compound MB327 against soman poisoning – Importance of experimental end point

2017 Toxicology Letters
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The potential role of bioscavenger in the medical management of nerve-agent poisoned casualties.

2016 Chemico-Biological Interactions
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Reversal of cardiac vagal effects of physostigmine by adjunctive muscarinic blockade

2016 Neurotoxicology
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Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines.

2015 PLOS ONE
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Affinities of bispyridinium non-oxime compounds to [3H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length

2013 Chemico-Biological Interactions
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1,1′-(Propane-1,3-diyl)bis(4-tert-butylpyridinium) di(methanesulfonate) protects guinea pigs from soman poisoning when used as part of a combined therapy

2012 MedChemComm
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Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM5)

2012 Drug Testing and Analysis
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