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Anne M. Vrabel

Mayo Clinic

32

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547

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A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition.

2021 Journal of Biological Chemistry
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GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.

2020 Biochemical Journal
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TFII-I-mediated polymerase pausing antagonizes GLI2 induction by TGFβ.

2020 Nucleic Acids Research
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Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells

2015 Journal of Immunology
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Waldenström Macroglobulinemia Cells GLI 2-Mediated Regulation of Ig Secretion in Underlies α Modulation of the IL-6 Receptor

2015
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The Transcription Factor GLI1 Interacts with SMAD Proteins to Modulate Transforming Growth Factor β-Induced Gene Expression in a p300/CREB-binding Protein-associated Factor (PCAF)-dependent Manner

2014 Journal of Biological Chemistry
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The Transcription Factor GLI1 Mediates TGFβ1 Driven EMT in Hepatocellular Carcinoma via a SNAI1-Dependent Mechanism

2012 PLOS ONE
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GLI1 Inhibition Promotes Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells

2012 Cancer Research
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TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways

2011 PLOS ONE
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MYOCILIN LEVELS IN PRIMARY OPEN-ANGLE GLAUCOMA AND PSEUDOEXFOLIATION GLAUCOMA HUMAN AQUEOUS HUMOR

2010 Journal of Glaucoma
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