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Angelina J. Vince

Walter and Eliza Hall Institute of Medical Research

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The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation.

2021 Nature Communications
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The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release

2019 Journal of Immunology
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XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation

2017 Cell Reports
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