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Sharlyn J. Mazur

National Institutes of Health

49

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Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA

2021 Nucleic Acids Research
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Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses

2021 Nature Communications
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A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.

2018 Journal of Biological Chemistry
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Trapped human PPM1A-phosphopeptide complex: structural implications for regulation of PPM metal- dependent protein phosphatase activity

2018 Journal of Biological Chemistry
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Chemical Features Important for Activity in a Class of Inhibitors Targeting the Wip1 Flap Subdomain

2018 ChemMedChem
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Abstract 3867: Epigenetic siRNA and chemical screens identify SETD8 inhibition as a therapeutic strategy to reactivate p53 in high-risk neuroblastoma

2017 Cancer Research
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The Area Between Exchange Curves as a Measure of Conformational Differences in Hydrogen-Deuterium Exchange Mass Spectrometry Studies

2017 Journal of the American Society for Mass Spectrometry
- Sharlyn J. Mazur
- Daniel P. Weber
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Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma

2017 Cancer Cell
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An Acetyl-Methyl Switch Drives a Conformational Change in p53.

2015 Structure
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The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.

2014 Oncogene
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