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Hongtao Wang

University of Southern California

13

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N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing

2008 Molecular Cancer Therapeutics
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Fenretinide increased ceramides through progressive de novo synthesis and inhibition of sphingomyelin synthesis in a neuroblastoma cell line

2006 Cancer Research
- Hongtao Wang
- Barry J. Maurer
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Cytotoxic drugs induced sphingosine kinase I mRNA and showed synergistic cytotoxicity when combined with sphingosine kinase inhibitors in multi-drug resistant neuroblastoma cell lines.

2006 Cancer Research
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Uptake and metabolism of safingol in human neuroblastoma and leukemia cell lines

2004 Cancer Research
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Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the vitamin D3 analog EB 1089

2004 The Journal of Steroid Biochemistry and Molecular Biology
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Increasing intracellular ceramide: an approach that enhances the cytotoxic response in prostate cancer cells☆

2003 Urology
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Enhanced de novo ceramide generation through activation of serine palmitoyltransferase by the P-glycoprotein antagonist SDZ PSC 833 in breast cancer cells.

2002 Molecular Cancer Therapeutics
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Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT388-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF

2001
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N-(4-hydroxyphenyl)retinamide elevates ceramide in neuroblastoma cell lines by coordinate activation of serine palmitoyltransferase and ceramide synthase

2001 Cancer Research
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