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Roheeth Kumar Pavana

Duquesne University

13

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185

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Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors

2020 ACS Medicinal Chemistry Letters
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Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents

2017 Bioorganic & Medicinal Chemistry
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A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model

2015 BMC Cancer
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Abstract 1622: Design and preclinical evaluation of single agents with tubulin and multiple receptor tyrosine kinase inhibition

2014 Cancer Research
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Abstract 5682: Design and preclinical evaluation of single agents with combination chemotherapy potential.

2013 Cancer Research
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Novel Water-Soluble Substituted Pyrrolo[3,2-d]pyrimidines: Design, Synthesis, and Biological Evaluation as Antitubulin Antitumor Agents

2012 Pharmaceutical Research
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Heteroaryl-substuted semicarbazones : Synthesis and anticonvulsant activity of N-(3-methylpyridin-2-yl)-substituted semicarbazones

2006 Journal of Heterocyclic Chemistry
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Heteroaryl-substuted semicarbazones : Synthesis and anticonvulsant activity of N-(3-methylpyridin-2-yl)-substituted semicarbazones

2006 Journal of Heterocyclic Chemistry
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Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.

2005 Journal of Medicinal Chemistry
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