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Lei Ma

Merck & Co.

19

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480

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MK-7622: A First-in-Class M1 Positive Allosteric Modulator Development Candidate

2018 ACS Medicinal Chemistry Letters
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Consistency of BACE inhibitor-mediated brain amyloid production inhibition by MK-8931 in Alzheimer’s disease patients and healthy young adults

2013 Alzheimers & Dementia
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The novel BACE inhibitor MK-8931 dramatically lowers CSF beta-amyloid in patients with mild-to-moderate Alzheimer's disease

2013 Alzheimers & Dementia
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The Novel BACE Inhibitor MK-8931 Dramatically Lowers CSF A Peptides in Healthy Subjects: Results from a Rising Single Dose Study (PL02.004)

2012 Neurology
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A study to evaluate the pharmacokinetics and pharmacodynamics of single and multiple oral doses of the novel BACE inhibitor MK-8931 in Japanese subjects

2012 Alzheimers & Dementia
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Effect of posaconazole on the pharmacokinetics of simvastatin and midazolam in healthy volunteers.

2012 Expert Opinion on Drug Metabolism & Toxicology
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Pharmacokinetics and pharmacodynamics of the novel PAR-1 antagonist vorapaxar in patients with end-stage renal disease.

2012 European Journal of Clinical Pharmacology
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Safety and pharmacokinetics of the novel BACE inhibitor MK-8931 in healthy subjects following single- and Multiple-Dose administration

2012 Alzheimers & Dementia
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Development and application of a mathematical model of modulation of cerebrospinal fluid Aβ40 after treatment with gamma- and beta-secretase inhibitors

2012 Alzheimers & Dementia
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A new solid oral tablet formulation of posaconazole: a randomized clinical trial to investigate rising single- and multiple-dose pharmacokinetics and safety in healthy volunteers

2012 Journal of Antimicrobial Chemotherapy
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Citations (118)