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Craig E. Masse

Boston University

43

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INHIBITEURS DE TYK2 ET LEURS UTILISATIONS

2019
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Accelerating drug discovery through tight integration of expert molecular design and predictive scoring

2017 Current Opinion in Structural Biology
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Anti‐leukaemic activity of the TYK2 selective inhibitor NDI‐031301 in T‐cell acute lymphoblastic leukaemia

2017 British Journal of Haematology
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Anti-Leukemic Activity of the TYK2 Selective Inhibitor Ndi-031301 in T-Cell Acute Lymphoblastic Leukemia

2016 Blood
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Identification of highly potent and selective Tyk2 inhibitors for the treatment of autoimmune diseases through structure-based drug design (THER2P.961)

2015 Journal of Immunology
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Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field

2015 Journal of the American Chemical Society
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Escherichia coli RNA polymerase in complex with squaramide compound 8.

2015
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Escherichia coli RNA polymerase in complex with squaramide compound 14 (N-[3,4-dioxo-2-(4-{[4-(trifluoromethyl)benzyl]amino}piperidin-1-yl)cyclobut-1-en-1-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide)

2015
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Escherichia coli RNA polymerase in complex with Myxopyronin B

2015
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Dérivés de composés amino-hétéroaryles substitués par des pyrazoles

2012
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