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Roddy S. O’Connor

University of Pennsylvania

48

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Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease.

2021 Frontiers in Immunology
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Enhancing CAR T Function with the Engineered Secretion of C. Perfringens Neuraminidase.

2021 Molecular Therapy
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Beyond the Lactate Paradox: How Lactate and Acidity Impact T Cell Therapies against Cancer.

2021 Antibodies
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CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy.

2021 Nature Communications
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Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.

2021 Nature Medicine
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Lingering effects of chemotherapy on mature T cells impair proliferation.

2020 Blood Advances
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Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues.

2020 Open Biology
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Novel media formulations to enhance Chimeric Antigen Receptor (CAR) T-cell potency and anti-tumor cell function for adoptive immunotherapy

2020 Cytotherapy
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4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling

2020 Science Signaling
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Quantitative prospective and retrospective mass spectrometry of lactoyl-CoA in mammalian cells and tissues

2020 bioRxiv
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