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Stacey Fynch

St. Vincent's Institute of Medical Research

28

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513

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Elevated Neuropeptide Y1 Receptor Signaling Contributes to β-cell Dysfunction and Failure in Type 2 Diabetes

2021 bioRxiv
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IL-17F induces inflammation, dysfunction and cell death in mouse islets.

2020 Scientific Reports
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The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice

2020 Frontiers in Immunology
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ABCA12 regulates insulin secretion from β-cells.

2020 EMBO Reports
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IL-21 regulates SOCS1 expression in autoreactive CD8 + T cells but is not required for acquisition of CTL activity in the islets of non-obese diabetic mice

2019 Scientific Reports
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Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice

2019 Cell death discovery
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Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in Non-Obese Diabetic Mice

2017 Diabetes
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The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

2017 Cell Death and Disease
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Granzyme A-deficiency breaks immune tolerance and promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway

2017 Diabetes
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Isolation and Culture of the Islets of Langerhans from Mouse Pancreas

2016
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