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Egon Deyaert

Vrije Universiteit Brussel

18

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631

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Nanobodies to allosterically modulate the GTPase activity of a LRRK2 homolog.

2021
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Allosteric modulation of the GTPase activity of a bacterial LRRK2 homologue by conformation-specific Nanobodies.

2020 Biochemical Journal
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Structure and nucleotide-induced conformational dynamics of the Roco protein

2018 Biochemical Journal
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Use of conformation and domain specific nanobodies to elucidate the working mechanism and structure of LRRK2 and homologous Roco proteins.

2018
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Crystal structure of the LRR-Roc-COR domain of the Chlorobium tepidum Roco protein

2018
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New Insights in the Nucleotide dependent Conformational Cycle of Roco Proteins and the Parkinson’s Disease-associated Protein LRRK2.

2018
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Structure and nucleotide-induced conformational dynamics of theChlorobium tepidumRoco protein.

2018 Biochemical Journal
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Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue

2016 Nucleic Acids Research
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Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts

2016 Proceedings of the National Academy of Sciences of the United States of America
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Conformational specific nanobodies for Chlorobium tepidum Roco protein.

2016
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