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Suzie J. Scales

Genentech

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Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant

2020 Journal of Immunological Methods
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Domain-Specific Antibodies Reveal Differences in the Membrane Topologies of Apolipoprotein L1 in Serum and Podocytes.

2020 Journal of The American Society of Nephrology
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An in vitro FcRn-dependent transcytosis assay as a screening tool for predictive assessment of non-specific clearance of antibody therapeutics in humans

2019 mAbs
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Development of a cysteine-conjugatable disulfide FRET probe: Influence of Charge on Linker Cleavage and Payload Trafficking for an anti-HER2 antibody conjugate

2019 Bioconjugate Chemistry
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Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members

2019 mAbs
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Preclinical Efficacy of an Antibody–Drug Conjugate Targeting Mesothelin Correlates with Quantitative 89Zr-ImmunoPET

2017 Molecular Cancer Therapeutics
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Phase I Study of DMOT4039A, an Antibody-Drug Conjugate Targeting Mesothelin, in Patients with Unresectable Pancreatic or Platinum-Resistant Ovarian Cancer

2016 Molecular Cancer Therapeutics
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The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels

2015 Journal of Biological Chemistry
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HAND2 Targets Define a Network of Transcriptional Regulators that Compartmentalize the Early Limb Bud Mesenchyme

2014 Developmental Cell
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DropArray™, a Wall-Less 96-Well Plate for Uptake and Immunofluorescence Microscopy, Confirms CD22 Recycles

2014 Traffic
- Gladys Ingle
- Suzie J. Scales
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Citations (9)