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Kjerstin M. Owens

Roswell Park Cancer Institute

21

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Abstract 1494: Interethnic germline variants in mitochondrial DNA polymerase (POLG1) induce mitochondrial dysfunction and confer tumorigenic properties

2017 Cancer Research
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Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome.

2015 PLOS ONE
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Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties

2015 PLOS ONE
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Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2−• and H2O2

2012 Free Radical Biology and Medicine
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Cellular model of warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin

2011 PLOS ONE
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Sensitivity to Low-Dose/Low-LET Ionizing Radiation in Mammalian Cells Harboring Mutations in Succinate Dehydrogenase Subunit C is Governed by Mitochondria-Derived Reactive Oxygen Species

2011 Radiation Research
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Impaired OXPHOS Complex III in Breast Cancer

2011 PLOS ONE
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Genetic insights into Warburg Effect reveal tumor promoting function of UCP2

2011 Free Radical Biology and Medicine
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Distinct Functions of Evolutionary Conserved MSF1 and Late Embryogenesis Abundant (LEA)-like Domains in Mitochondria

2011 Journal of Biological Chemistry
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SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

2010 Cancer Cell
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