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Weirui Guo

University of Texas Southwestern Medical Center

10

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995

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FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination.

2016 Human Molecular Genetics
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Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice

2016 The Journal of Neuroscience
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Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice.

2016 Biological Psychiatry
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Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model

2015 Cell Reports
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Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

2012 Nature Neuroscience
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An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

2011 Nature Structural & Molecular Biology
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A Drosophila model for TDP-43 proteinopathy.

2010 Proceedings of the National Academy of Sciences of the United States of America
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Small RNA-directed DNA methylation and tumorigenesis

2006 Progress in Biochemistry and Biophysics
- Weirui Guo
- James Q Yin
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