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Carol C. Edwards

St. Jude Children's Research Hospital

51

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Carboxylesterases: General detoxifying enzymes.

2016 Chemico-Biological Interactions
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Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors

2013 Chemico-Biological Interactions
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Modulation of Esterified Drug Metabolism by Tanshinones from Salvia miltiorrhiza (“Danshen”)

2013 Journal of Natural Products
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Correction: Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme.

2012 PLOS ONE
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Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing

2011 ACS Chemical Biology
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Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme

2011 PLOS ONE
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Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11

2011 Biochemical Pharmacology
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Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles

2011 Biotechnology Progress
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Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2.

2010 Chemical Research in Toxicology
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Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin

2010 British Journal of Pharmacology
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Citations (44)