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Paul-Emmanuel Larchanché

university of lille

13

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83

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New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease

2019 Neurobiology of Disease
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New phenylaniline derivatives as modulators of amyloid protein precursor metabolism

2018 Bioorganic & Medicinal Chemistry
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Evaluation of three neutral capillary coatings for the determination of analyte-cyclodextrin binding constants by affinity capillary electrophoresis. Application to N,N⿲-disubstituted piperazine derivatives.

2016 Journal of Chromatography A
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Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands.

2015 European Journal of Medicinal Chemistry
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Chloroquine and chloroquinoline derivatives as models for the design of modulators of amyloid Peptide precursor metabolism.

2015 ACS Chemical Neuroscience
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Carboline- and phenothiazine-derivated heterocycles as potent SIGMA-1 protein ligands.

2015 European Journal of Medicinal Chemistry
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Methodology to access tetrahydrodipyridoimidazole derivatives

2012 Heterocycles
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Methodology to access tetrahydrodipyridoimidazole derivatives

2012 Heterocycles
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Buchwald reaction as the key step for the synthesis of metabolically more stable analogs of amodiaquine

2011 European Journal of Medicinal Chemistry
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Buchwald Reaction as the Key Step for the Synthesis of Metabolically More Stable Analogues of Amodiaquine.

2011 ChemInform
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