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Sebastien A. Gauthier

Nathan Kline Institute for Psychiatric Research

10

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553

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Neuroprotection mediated by cystatin C-loaded extracellular vesicles

2019 Scientific Reports
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A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients

2019 Neurobiology of Aging
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Cystatin C prevents neuronal loss and behavioral deficits via the endosomal pathway in a mouse model of down syndrome

2018 Neurobiology of Disease
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A Method for Isolation of Extracellular Vesicles and Characterization of Exosomes from Brain Extracellular Space

2017 Methods of Molecular Biology
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Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities

2017 Acta neuropathologica communications
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In vitro assays measuring protection by proteins such as cystatin C of primary cortical neuronal and smooth muscle cells.

2012 Methods of Molecular Biology
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Murine cerebrovascular cells as a cell culture model for cerebral amyloid angiopathy: isolation of smooth muscle and endothelial cells from mouse brain.

2012 Methods of Molecular Biology
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The exosome-secretory pathway transports amyloid precursor protein carboxyl terminal fragments from the cell into the brain extracellular space

2012 Journal of Biological Chemistry
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Protective mechanisms by cystatin C in neurodegenerative diseases.

2011 Frontiers in Bioscience
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Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines

2010 PLOS ONE
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