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Brigitte Demers

19

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434

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A phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours

2019 British Journal of Cancer
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Use of PBPK modeling for drug–drug interactions prediction of rifapentine on other drugs by induction of CYP3A4/5 and CYP2B6

2018 Drug Metabolism and Pharmacokinetics
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First‐in‐human trial of the PI3Kβ‐selective inhibitor SAR260301 in patients with advanced solid tumors

2018 Cancer
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A phase I study of ombrabulin (O) combined with bevacizumab (B) in patients with advanced solid tumors (NCT01193595).

2017 Journal of Clinical Oncology
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Predictive biomarkers of response to the tubulin-binding agent DM4 in colorectal cancer preclinical models

2016 European Journal of Cancer
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First-in-human phase I trial of the anti-CEACAM5 antibody–drug conjugate SAR408701 in patients with advanced solid tumors (NCT02187848)

2016 European Journal of Cancer
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First-in-human phase I trial of the PI3Kb-selective inhibitor SAR260301 in patients with advanced solid tumors (NCT01673737).

2015 Journal of Clinical Oncology
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Abstract 3258: Discovery and characterization of SAR260301, a novel PI3Kβ-selective inhibitor in clinical development for the treatment of PTEN-deficient tumors .

2013 Cancer Research
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Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer

2012 Clinical Cancer Research
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Early quantitative evaluation of a tumor vasculature disruptive agent AVE8062 using dynamic contrast-enhanced ultrasonography.

2008 Investigative Radiology
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Citations (75)