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Jason Hill

Cleveland Clinic

24

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Discovery and optimization of a series of 3-(3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amines: orally bioavailable, selective, and potent ATP-independent Akt inhibitors.

2012 Journal of Medicinal Chemistry
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Abstract LB-1: Discovery and optimization of orally bioavailable, selective and potent ATP-independent Akt inhibitors

2012 Cancer Research
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Inhibition of proteasome activity by bortezomib in renal cancer cells is p53 dependent and VHL independent

2009 Anticancer Research
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Composés de pyrazolo[3,4-b]pyridine substitués

2009
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Molecules de liaison de ligand erbb bivalentes et procedes destines a leur preparation et leur utilisation

2007
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560 POSTER Inhibition of erbB 1/2 by small molecule tyrosine kinase inhibitors, but not trastuzumab, affects metabolic pathways: implications to cardiac toxicity

2006 Ejc Supplements
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Downregulation of topoisomerase IIβ in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest

2006 Leukemia
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493 POSTER Down regulation of topoisomerase IIβ in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest

2006 Ejc Supplements
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Down-Regulation of p53 by Double-Stranded RNA Modulates the Antiviral Response

2005 Journal of Virology
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Targeted si-RNA mediated down-regulation of topoisomerase II α or β isozymes defines selectivity to inhibitors of the enzyme

2005 Cancer Research
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