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Philip Nugent

Laboratory of Molecular Biology

4

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A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.

1998 Protein Engineering
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Expression and characterisation of chymosin pH optima mutants produced in Trichoderma reesei

1993 Journal of Biotechnology
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Multidisciplinary cycles for protein engineering: site-directed mutagenesis and X-ray structural studies of aspartic proteinases.

1992 Scandinavian Journal of Clinical & Laboratory Investigation
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Protein engineering of the surface loops of chymosin

1991 Biochemical Society Transactions
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Citations (3)