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Pin-Xian Xu

Icahn School of Medicine at Mount Sinai

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Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm.

2021 Proceedings of the National Academy of Sciences of the United States of America
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Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.

2021 Journal of The American Society of Nephrology
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Eya2 expression during mouse embryonic development revealed by Eya2 lacZ knockin reporter and homozygous mice show mild hearing loss.

2021 Developmental Dynamics
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Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium

2020 Nucleic Acids Research
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SIX1/EYA1 are novel liver damage biomarkers in chronic hepatitis B and other liver diseases

2020
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Brg1 controls neurosensory cell fate commitment and differentiation in the mammalian inner ear

2018 bioRxiv
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[Production of transgenic mice for alpha-1 antitrypsin deficiency disease].

2018 Chinese Journal of Hepatology
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EYA1's conformation-specificity in dephosphorylating phosphothreonine in Myc and its activity on Myc stabilization in breast cancer

2017 Molecular and Cellular Biology
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Author response: An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis

2017 eLife
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Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium

2017 PLOS Genetics
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Citations (26)