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Qiang Zeng

Walter Reed Army Institute of Research

13

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288

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Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.

2020 Journal of Medicinal Chemistry
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Improving Relative Bioavailability of Oral Imidazolidinedione by Reducing Particle Size Using Homogenization and Ultra-Sonication

2019 Military Medicine
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Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

2017 Malaria Research and Treatment
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Comparative Susceptibility of Different Mouse Strains to Liver-Stage Infection With Plasmodium berghei Sporozoites Assessed Using In Vivo Imaging

2017 Military Medicine
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Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

2014 Malaria Journal
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The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models

2014 European Journal of Drug Metabolism and Pharmacokinetics
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Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections

2014 Malaria Journal
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Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum

2011 European Journal of Drug Metabolism and Pharmacokinetics
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Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice

2011 Malaria Journal
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Embryotoxicity of artesunate in animal species related to drug tissue distribution and toxicokinetic profiles.

2008 Birth Defects Research Part B-developmental and Reproductive Toxicology
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Citations (21)