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Hashem A. Dbouk

Albert Einstein College of Medicine

24

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Venous malformations: PIK3CA mutations guide new treatments

2016 Oncotarget
- Hashem A. Dbouk
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Identification of the Rab5 binding site in p110β: assays for PI3Kβ binding to Rab5.

2015 Methods of Molecular Biology
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Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK.

2014 Proceedings of the National Academy of Sciences of the United States of America
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G protein-coupled receptors and the regulation of autophagy.

2014 Trends in Endocrinology and Metabolism
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Abstract 10373: Characterization of WNK-PI3-Kinase Interaction and its Impact on Signaling by Both Enzymes

2013 Circulation
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Characterization of a Tumor-Associated Activating Mutation of the p110β PI 3-Kinase

2013 PLOS ONE
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Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).

2013 Proceedings of the National Academy of Sciences of the United States of America
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Novel approaches to inhibitor design for the p110β phosphoinositide 3-kinase

2013 Trends in Pharmacological Sciences
- Hashem A. Dbouk
- Jonathan M. Backer
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G protein-coupled receptor-mediated activation of p110b by Gβγ is required for cellular transformation and invasiveness

2012 Science Signaling
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PI3Kβ downstream of GPCRs - crucial partners in oncogenesis.

2012 Oncotarget
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