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Yingyi Chen

Shanghai Jiao Tong University

30

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610

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Reply to: Binding site for MDL-801 on SIRT6.

2021 Nature Chemical Biology
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Reply to: Binding site for MDL-801 on SIRT6.

2021 Nature Chemical Biology
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Identification of an allosteric hotspot for additive activation of PPARγ in antidiabetic effects

2021 Chinese Science Bulletin
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A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis.

2021 Acta Pharmaceutica Sinica B
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Identification of an allosteric hotspot for additive activation of PPARγ in antidiabetic effects

2021 Chinese Science Bulletin
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Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators

2020 Acta Pharmaceutica Sinica B
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Small-molecule activating SIRT6 elicits therapeutic effects and synergistically promotes anti-tumor activity of vitamin D3 in colorectal cancer.

2020 Theranostics
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A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

2020 Acta Pharmaceutica Sinica B
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Unraveling allosteric landscapes of allosterome with ASD

2019 Nucleic Acids Research
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Identification of a cellularly active SIRT6 allosteric activator.

2018 Nature Chemical Biology
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