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Kevin J. Hodgetts

Brigham and Women's Hospital

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Barcoded viral tracing of single-cell interactions in central nervous system inflammation.

2021 Science
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Short-duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy.

2021
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Nanotherapeutic approaches to overcome distinct drug resistance barriers in models of breast cancer.

2021 Nanophotonics
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Short duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy

2020 bioRxiv
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Synthesis of the HIF-2α translation inhibitor compound 76 via a Japp-Klingemann coupling

2019 Tetrahedron Letters
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Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer’s disease: a preclinical study in rTg4510 mice

2019 Alzheimer's Research & Therapy
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A NOVEL SMALL-MOLECULE ACTIVATOR OF GLUTAMATE TRANSPORTER EAAT2 DELAYS DISEASE PROGRESSION IN A TAUOPATHY MODEL OF ALZHEIMER’S DISEASE

2018 Alzheimers & Dementia
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Small Molecule Approaches to Upregulate SMN Expression From the SMN2 Locus

2017
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Optimization of a series of heterocycles as survival motor neuron gene transcription enhancers

2017 Bioorganic & Medicinal Chemistry Letters
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Discovery of a Small Molecule Probe That Post-Translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy

2017
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