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Robert S. Lahue

National University of Ireland, Galway
Eppley Institute for Research in Cancer and Allied Diseases

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SPYing on triplet repeat expansions: Insights into FAN1-MLH1 interaction and regulation.

2021 Cell Reports
- Robert S. Lahue
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HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions.

2020 Proceedings of the National Academy of Sciences of the United States of America
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New developments in Huntington’s disease and other triplet repeat diseases: DNA repair turns to the dark side

2020
- Robert S. Lahue
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Assessing Triplet Repeat Expansions in Human SVG-A Cell Culture

2020 Methods of Molecular Biology
- Gregory M. Williams
- Robert S. Lahue
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A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington’s disease mice

2017 Scientific Reports
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MutSβ Abundance and Msh3 ATP Hydrolysis Activity Are Important Drivers of CTG•CAG Repeat Expansions

2017 Nucleic Acids Research
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The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.

2016 DNA Repair
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Nucleotide excision repair and the 26S proteasome function together to promote trinucleotide repeat expansions.

2014 DNA Repair
- Claire Concannon
- Robert S. Lahue
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RTEL1 Inhibits Trinucleotide Repeat Expansions and Fragility

2014 Cell Reports
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Trinucleotide repeat expansions catalyzed by human cell-free extracts

2013 Cell Research
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Citations (15)