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Karen Elizabeth Lackey

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CHAPTER 27:Lessons Learned From the Discovery and Development of Lapatinib/Tykerb

2014
- G. Stuart Cockerill
- Karen Elizabeth Lackey
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The discovery of potent and selective 4-aminothienopyridines as B-Raf kinase inhibitors

2013 Bioorganic & Medicinal Chemistry Letters
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Lapatinib, an Anticancer Kinase Inhibitor

2010
- Karen Elizabeth Lackey
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Tykerb Discovery: A Dual EGFR and ERBB2 Tyrosine Kinase Inhibitor

2009
- Karen Elizabeth Lackey
- G. Stuart Cockerill
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Drug Discoveries by Gene Family

2008
- Karen Elizabeth Lackey
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The Discovery of Substituted 4-(3-Hydroxyanilino)-quinolines as Potent RET Kinase Inhibitors.

2008 ChemInform
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RET Activation Inhibits Doxorubicin-induced Apoptosis in SK-N-MC Cells

2008 Anticancer Research
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The discovery of substituted 4-(3-hydroxyanilino)-quinolines as potent RET kinase inhibitors.

2007 Bioorganic & Medicinal Chemistry Letters
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Aza-stilbenes as potent and selective c-RAF inhibitors.

2006 Bioorganic & Medicinal Chemistry Letters
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Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series

2006 Bioorganic & Medicinal Chemistry Letters
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