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Gee-Hong Kuo
Gee-Hong Kuo
Janssen Pharmaceutica
Chemistry
Biochemistry
Organic chemistry
Diabetes mellitus
orally active
7
Papers
39
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5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as Potent and Orally Bioavailable SGLT1 and SGLT2 Dual Inhibitors
2020
Bioorganic & Medicinal Chemistry Letters
Guozhang Xu
Fuyong Du
Gee-Hong Kuo
June Zhi Xu
Yin Liang
Keith T. Demarest
Michael David Gaul
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Citations (1)
Potent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in Rodents
2018
Journal of Pharmacology and Experimental Therapeutics
Fuyong Du
Simon A. Hinke
Cassandre R. Cavanaugh
David Polidori
Nathanial Wallace
Thomas Kirchner
Matthew Jennis
Wensheng Lang
Gee-Hong Kuo
Micheal D. Gaul
James Lenhard
Keith T. Demarest
Nadim J. Ajami
Yin Liang
Pamela J. Hornby
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Citations (11)
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors
2018
Bioorganic & Medicinal Chemistry Letters
Guozhang Xu
Michael David Gaul
Gee-Hong Kuo
Fuyong Du
June Zhi Xu
Nathaniel Wallace
Simon A. Hinke
Thomas Kirchner
Jose Silva
Norman D. Huebert
Seunghun Lee
William V. Murray
Yin Liang
Keith T. Demarest
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Metabolic tracing of monoacylglycerol acyltransferase-2 activity in vitro and in vivo.
2017
Analytical Biochemistry
Jenson Qi
Wensheng Lang
Margery A. Connelly
Fuyong Du
Yin Liang
Gary W. Caldwell
Tonya Martin
Michael K. Hansen
Gee-Hong Kuo
Michael David Gaul
Alessandro Pocai
Seunghun Lee
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Synthesis of β-Substituted Cyclic Enones via Phosphonium Salt-Activated, Palladium-Catalyzed Cross-Coupling of Cyclic 1,3-Diones.
2016
ChemInform
Shyh-Ming Yang
Gee-Hong Kuo
Michael David Gaul
William V. Murray
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