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Christine O’Keefe

Cleveland Clinic

25

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217

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A MICROFLUIDIC DIGITAL MELT PLATFORM FOR SENSITIVE BIOMARKER ANALYSIS AND PARALLELIZED PROFILING OF MOLECULAR HETEROGENEITY

2020
- Christine O’Keefe
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Use of single polymorphism arrays (SNP-A) to modify prognostic scoring systems for myelodysplastic syndromes.

2017 Journal of Clinical Oncology
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Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

2012 PLOS ONE
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Defining the Topography of Deletion 5q Using SNP-A Identifies Patients with More Aggressive Disease and Correlates with Additional Lesions

2011 Blood
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Permissive Conditions for Evolution of PNH Clones Are Characterized by Overproduction of IFN-γ by Clonal CD4 and CD8 T Cells, Fas-L by CTLs, and Promoted by Immunogenetic Background

2008 Blood
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Definition of Commonly Deleted Regions and Identification of Candidate Genes of Chromosome 20 in Myeloid Malignancies Using Genome-Wide Single Nucleotide Polymorphism (SNP) Array.

2008 Blood
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SNP-A Based Karyotyping Facilitates Improved Mapping of Deletions and Uniparental Disomy within the Long Arm of Chromosome 5 in Myeloid Disorders.

2007 Blood
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Non Synonymous SNP-Array-Based Disease Association Analysis in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria.

2007 Blood
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Analysis of Immunogenetic Factors in Myelodysplastic Syndromes (MDS) Reveals Potential Pathogenic Role Cytokine Genotypes Such as TGF-β.

2007 Blood
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Impact of cytokine polymorphism in myelodysplastic syndromes (MDS).

2007
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