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Jonathan Basil Fitzgerald

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Abstract A188: T-cell priming with Deep IL-15 improves preclinical safety compared to systemic IL-15, and increases in vivo persistence and activity

2019 Cancer immunology research
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Delivery of TLR7 agonists by Deep-Primed (TM) T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity

2019 Journal for ImmunoTherapy of Cancer
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Abstract 2244: DeepIL-15 primed T cells synergize with PD-L1 blockade to overcome resistance to checkpoint immunotherapy

2019 Cancer Research
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Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia

2019 Molecular Imaging and Biology
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Abstract 3577: Application of deep IL-15 backpacks to human T cells demonstrates tunable loading with enhanced cell proliferation and antitumor activity

2018 Cancer Research
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Liposomal Irinotecan Achieves Significant Survival and Tumor Burden Control in a Triple Negative Breast Cancer Model of Spontaneous Metastasis

2018 Molecular Pharmaceutics
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Photodynamic priming mitigates chemotherapeutic selection pressures and improves drug delivery

2018 Cancer Research
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Companion Diagnostic 64Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines

2018 Theranostics
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P1.07-006 Preclinical Support for Evaluation of Irinotecan Liposome Injection (nal-IRI, MM-398) in Small Cell Lung Cancer: Topic: Drug Treatment Alone and in Combination with Radiotherapy

2017 Journal of Thoracic Oncology
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Abstract 5151: Nanoliposomal irinotecan (nal-IRI, MM-398) has greater anti-tumor activity than topotecan and irinotecan in mouse models of small cell lung cancer

2017 Cancer Research
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