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Vikash Reebye

Imperial College London

42

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MTL-CEBPA Combined with Immunotherapy or RFA Enhances Immunological Anti-Tumor Response in Preclinical Models

2021 International Journal of Molecular Sciences
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515 A phase 1 study of myeloid modulating agent MTL-CEBPA in combination with pembrolizumab in adult patients with advanced solid tumours

2021 Journal for ImmunoTherapy of Cancer
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Abstract 1730: Up-regulation of C/EBPα inhibits suppressive activity of myeloid cells and potentiates antitumor response in mice and cancer patients

2021 Cancer Research
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Up-regulation of C/EBPα inhibits suppressive activity of myeloid cells and potentiates antitumor response in mice and cancer patients

2021 Clinical Cancer Research
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Small activating RNA therapeutic MTL-CEBPA in patients with advanced liver cancer: a first-in-human, multi-centre, open-label, phase I trial

2020 Clinical Cancer Research
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Liver activation of Hepatocellular Nuclear Factor-4α by small activating RNA rescues dyslipidemia and improves metabolic profile

2019 Molecular therapy. Nucleic acids
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Anti-inflammatory Activity of MTL-CEBPA, a Small Activating RNA Drug, in LPS-Stimulated Monocytes and Humanized Mice

2019 Molecular Therapy
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Targeted delivery of C/EBPα-saRNA by RNA aptamers shows anti-tumor effects in a mouse model of advanced pancreatic ductal adenocarcinoma

2019 Molecular therapy. Nucleic acids
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Mechanisms involved in the activation of C/EBPα by small activating RNA in hepatocellular carcinoma

2019 Oncogene
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Abstract 3211: MTL-CEBPA combined with radiofrequency ablation and immunotherapy enhances immunological anti-tumour response in an HCC mouse model

2019 Immunology
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