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Erwin Coesemans

Johnson & Johnson Pharmaceutical Research and Development

10

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Design and Synthesis of a Series of Piperazine‐1‐carboxamidine Derivatives with Antifungal Activity Resulting from Accumulation of Endogenous Reactive Oxygen Species

2009 ChemMedChem
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Pharmacological profile of JNJ-27141491 [(S)-3-[3,4-difluorophenyl)-propyl]-5-isoxazol-5-yl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxyl acid methyl ester], as a noncompetitive and orally active antagonist of the human chemokine receptor CCR2.

2008 Journal of Pharmacology and Experimental Therapeutics
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Discovery of Potent, Orally Bioavailable Small-Molecule Inhibitors of the Human CCR2 Receptor

2008 ChemMedChem
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2-Mercaptoimidazoles, a new class of potent CCR2 antagonists

2005 Bioorganic & Medicinal Chemistry Letters
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Antagonistes des recepteurs ccr2 a base de mercaptoimidazoles

2004
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6-azauracil derivatives which inhibit interleukin-5.

2000
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