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Sapna Gupta

Fox Chase Cancer Center

33

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876

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Analysis of the Qatari R336C Cystathionine β-Synthase Protein in Mice

2019 Journal of Inherited Metabolic Disease
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In silico and in vivo models for Qatari-specific classical homocystinuria as basis for development of novel therapies

2019 Human Mutation
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S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice

2018 Molecular genetics and metabolism reports
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NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast derived nutritional supply and immunosuppression

2018 bioRxiv
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Homocysteine modulates 5-lipoxygenase expression level via DNA methylation

2017 Aging Cell
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The c.797 G>A (p.R266K) cystathionine β-synthase mutation causes homocystinuria by affecting protein stability

2017 Human Mutation
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Lack of global epigenetic methylation defects in CBS deficient mice

2017 Journal of Inherited Metabolic Disease
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Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice

2016 Journal of Inherited Metabolic Disease
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Abstract 4785: Deficiency of cystathionine beta synthase gene does not affect tumor formation and survival of Eμ-myc mice

2015 Cancer Research
- Sapna Gupta
- Warren D. Kruger
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High homocysteine induces betaine depletion.

2015 Bioscience Reports
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