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Ed Casson
Ed Casson
AstraZeneca
Medicine
Pharmacology
Pharmacokinetics
Tolerability
in patient
3
Papers
15
Citations
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A Phase 1, open-label, multicentre study to compare the capsule and tablet formulations of AZD5363 and explore the effect of food on the pharmacokinetic exposure, safety and tolerability of AZD5363 in patients with advanced solid malignancies: OAK
2018
Cancer Chemotherapy and Pharmacology
Emma Dean
Udai Banerji
Jan H. M. Schellens
Matthew G Krebs
Begona Jimenez
Emilie M.J. van Brummelen
Christopher Bailey
Ed Casson
Diana Cripps
Marie Cullberg
Stephen Evans
Andrew Foxley
Justin P.O. Lindemann
Paul Rugman
Nigel Phillip Taylor
Guy Turner
James Yates
Peter Lawrence
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Citations (8)
A pharmacokinetically (PK) and pharmacodynamically (PD) driven phase I trial of the pan-AKT inhibitor AZD5363 with expansion cohorts in PIK3CA mutant breast and gynecological cancers.
2015
Journal of Clinical Oncology
Udai Banerji
Emma Dean
José Alejandro Pérez Fidalgo
Gerald Batist
Philippe L. Bedard
Benoit You
Shannon Neville Westin
Peter Kabos
Barry R. Davies
Paul Elvin
Peter Lawrence
James W.T. Yates
Helen Ambrose
Paul Rugman
Andrew Foxley
Shaista Salim
Ed Casson
Justin Lindemann
Jan H. M. Schellens
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Citations (5)
Results of OAK: A phase 1, open-label, multicentre study to compare two dosage forms of AZD5363 and to explore the effect of food on the pharmacokinetic (PK) exposure, safety, and tolerability of AZD5363 in patients with advanced solid malignancies.
2015
Journal of Clinical Oncology
Emma Dean
Udai Banerji
Jan H. M. Schellens
Matthew Krebs
Begoña Jiménez
Ruud van der Noll
Andrew Foxley
James W.T. Yates
Nigel Phillip Taylor
Steve Evans
Turner Guy
Ed Casson
Paul Rugman
Shaista Salim
Justin Lindemann
Peter Lawrence
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Citations (2)
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