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David R. Trentham

King's College London
Randall Division of Cell and Molecular Biophysics

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Q&A: Remembering Sir Andrew Huxley: Sir Andrew Huxley, ‘the most eminent physiologist of a generation’, passed away in May this year. We asked some Members who knew him to share some of their memories of the man who unravelled the propagation of the action potential and unveiled the sliding filament mechanism in striated muscle.

2012
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Orientation of the essential light chain region of myosin in skeletal muscle fibers determined by polarized fluorescence

2004 Biophysical Journal
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Crossbridge cycle in smooth muscle: kinetics assessed with flash photolysis and fluorescent probes.

2004 Journal of Muscle Research and Cell Motility
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Smooth muscle myosin: regulation and properties.

2004 Philosophical Transactions of the Royal Society B
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Comparison of two bifunctional rhodamine (BR) probes attached to troponin C (TnC) in skinned muscle fibers

2003 Biophysical Journal
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Photolytic cleavage of 1-(2-nitrophenyl)ethyl ethers involves two parallel pathways and product release is rate-limited by decomposition of a common hemiacetal intermediate

2003 Journal of the American Chemical Society
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Differential effects of Ca2+ and actively cycling cross-bridges on the orientation of the N- and C-terminal lobes of troponin C (TnC) in skeletal muscle

2003 Biophysical Journal
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Relative orientation of the N- and C-terminal lobes of myosin regulatory light chain (RLC) in skeletal muscle fibers

2001 Biophysical Journal
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