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Keshav Gopal

University of Alberta

45

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585

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Abstract 9054: Cell-Specific Regulation of the GATA-4/6 Transcription Factors by the Metabolic Enzyme PKM2 Provides Insight into a Biologic Function Essential for Cardiac Health and Survival

2021 Circulation
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The antianginal ranolazine does not confer beneficial actions against hepatic steatosis in male mice subjected to high-fat diet and streptozotocin induced type 2 diabetes

2021 Canadian Journal of Physiology and Pharmacology
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Abstract 11800: Inhibition of Pyruvate Dehydrogenase Kinase Does Not Improve Cardiac Abnormalities in a Mouse Model of Human Barth Syndrome

2021 Circulation
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FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity.

2021 Cell Reports
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Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation.

2021 American Journal of Physiology-heart and Circulatory Physiology
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379-P: Aldose Reductase Inhibition by AT-001 Prevents Diabetic Cardiomyopathy via Reducing Myocardial Fatty Acid Oxidation Rates

2021 Diabetes
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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.

2020 Cell Metabolism
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The GLP-1R agonist liraglutide increases myocardial glucose oxidation rates via indirect mechanisms and mitigates experimental diabetic cardiomyopathy

2020 Canadian Journal of Cardiology
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The Impact of Antidiabetic Therapies on Diastolic Dysfunction and Diabetic Cardiomyopathy

2020 Frontiers in Physiology
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The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity

2019 JCI insight
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