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Changxiang Shi
Changxiang Shi
University of Macau
Synthetic lethality
Biology
Cancer research
Cancer
Molecular biology
5
Papers
15
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Aurora kinase A, a synthetic lethal target for precision cancer medicine.
2021
Experimental and Molecular Medicine
Pui Kei Mou
Eun Ju Yang
Changxiang Shi
Guowen Ren
Shishi Tao
Joong Sup Shim
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Natural products targeting cancer cell dependency.
2021
The Journal of Antibiotics
Changxiang Shi
Eun Ju Yang
Shishi Tao
Guowen Ren
Pui Kei Mou
Joong Sup Shim
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Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression.
2020
Oncogene
Changxiang Shi
Eun Ju Yang
Yifan Liu
Pui Kei Mou
Guowen Ren
Joong Sup Shim
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Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT
2020
International Journal of Biological Sciences
Yifan Liu
Eun Ju Yang
Changxiang Shi
Pui Kei Mou
Baoyuan Zhang
Changjie Wu
Junfang Lyu
Joong Sup Shim
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Citations (6)
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics.
2020
Nature Communications
Junfang Lyu
Eun Ju Yang
Baoyuan Zhang
Changjie Wu
Lakhansing Pardeshi
Changxiang Shi
Pui Kei Mou
Yifan Liu
Kaeling Tan
Joong Sup Shim
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Citations (7)
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