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Irmgard Hofmann
Irmgard Hofmann
Novartis
Biology
PI3K/AKT/mTOR pathway
PTEN
In vivo
Programmed cell death
4
Papers
353
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Expression of the human cytomegalovirus pentamer complex for vaccine use in a CHO system
2015
Biotechnology and Bioengineering
Irmgard Hofmann
Yingxia Wen
Claudio Ciferri
Axel Schulze
Viola Fühner
Megan Leong
Andrea Gerber
Rachel Gerrein
Avishek Nandi
Anders Lilja
Andrea Carfi
Holger Laux
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Citations (29)
K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo
2012
PLOS ONE
Irmgard Hofmann
Andreas Weiss
Gaelle Elain
Maria Schwaederle
Dario Sterker
Vincent Romanet
Tobias Schmelzle
Albert Lai
Saskia M. Brachmann
Mohamed Bentires-Alj
Thomas M. Roberts
William R. Sellers
Francesco Hofmann
Sauveur-Michel Maira
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Citations (58)
Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells
2009
Proceedings of the National Academy of Sciences of the United States of America
Saskia M. Brachmann
Irmgard Hofmann
Christian Schnell
Christine Fritsch
Susan Wee
Heidi Lane
Shaowen Wang
Carlos Garcia-Echeverria
Sauveur-Michel Maira
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Citations (266)
Abstract B20: In vitro and in vivo antitumor activities of the dual PI3K/mTor inhibitor NVP‐BEZ235. Implications for patient stratification strategies
2009
Molecular Cancer Therapeutics
Michel Maira
Saskia M. Brachmann
Christine Fritsch
Irmgard Hofmann
Christian Schnell
Carlos Garcia-Echeverria
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