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Ewa Gogola

Netherlands Cancer Institute

22

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2070

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Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps.

2021 Molecular Cell
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Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps

2021 bioRxiv
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Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1-Deficient Cells by Increasing DNA Replication Stress

2020
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Resistance to PARP Inhibitors: Lessons from Preclinical Models of BRCA-Associated Cancer

2019
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Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas

2018 Cell Reports
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The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

2018 Cell Reports
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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

2018 Cancer Cell
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PO-495 Pi3k pathway upregulation mediates acquired resistance to platinum agents and polyadenoribose polymerase inhibitors (parpi) in brca1-methylated ovarian cancer (oc)

2018
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PO-496 Loss of parg drives parp inhibitor resistance in brca2-deficient mouse mammary tumours

2018
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BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance

2018 Nature Methods
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Citations (61)