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Polina V. Shcherbakova

Eppley Institute for Research in Cancer and Allied Diseases

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Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28.

2021 Genetics
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Abstract IA014: POLE mutations in endometrial cancer: Consequences and mechanisms

2021
- Polina V. Shcherbakova
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DNA polymerase δ proofreads errors made by DNA polymerase ε

2020 Proceedings of the National Academy of Sciences of the United States of America
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Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors

2020 Clinical and translational gastroenterology
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Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon

2019 Nature Communications
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Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae

2018 G3: Genes, Genomes, Genetics
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Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells

2017 Oncogene
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Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations

2017 Nucleic Acids Research
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DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures

2014 Nucleic Acids Research
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A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading

2014 Cancer Research
- Daniel P. Kane
- Polina V. Shcherbakova
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Citations (83)