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David Crich

University of Illinois at Chicago
Wayne State University
Institut de Chimie des Substances Naturelles

605

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17268

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Synthesis and Antibacterial Activity of Propylamycin Derivatives Functionalized at the 5''- and Other Positions with a View to Overcoming Resistance Due to Aminoglycoside Modifying Enzymes.

2021 ACS Infectious Diseases
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Synthesis of a Pseudotrisaccharide Suitable for Synthesis of Ring I Modified 4,5-2-Deoxystreptamine Type Aminoglycoside Antibiotics.

2020 Journal of Organic Chemistry
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Influence of protecting groups on O- and C-glycosylation with neuraminyl and ulosonyl dibutylphosphates

2020 Carbohydrate Research
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Use of hydroxylamines, hydroxamic acids, oximes and amines as nucleophiles in the zbiral oxidative deamination of N-Acetyl neuraminic acid. Isolation and characterization of novel mono- and disubstitution products

2020 Carbohydrate Research
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Stereospecific synthesis of methyl 2-amino-2,4-dideoxy-6S-deuterio-α-D-xylo-hexopyranoside and methyl 2-amino-2,4-dideoxy-6S-deuterio-4-propyl-α-d-glucopyranoside: Side chain conformation of the novel aminoglycoside antibiotic propylamycin

2020 Carbohydrate Research
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Stereocontrolled Synthesis of the Equatorial Glycosides of 3-Deoxy-d-manno-oct-2-ulosonic Acid: Role of Side Chain Conformation.

2020 Journal of the American Chemical Society
- Philemon Ngoje
- David Crich
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Predictive Analysis of the Side Chain Conformation of the Higher Carbon Sugars: Application to the Preorganization of the Aminoglycoside Ring 1 Side Chain for Binding to the Bacterial Ribosomal Decoding A Site.

2020 Journal of Organic Chemistry
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Glycoside Hydrolases Restrict the Side Chain Conformation of their Substrates to Gain Additional Transition State Stabilization.

2020 Journal of the American Chemical Society
- Jonathan Charles Kenneth Quirke
- David Crich
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Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease.

2020 ACS Infectious Diseases
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Synthesis, Cytotoxicity and Genotoxicity of 10-Aza-9-oxakalkitoxin, An N,N,O-Trisubstituted Hydroxylamine Analog, or Hydroxalog, of a Marine Natural Product.

2020 Journal of the American Chemical Society
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