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Antony J. Burton

Engineering and Physical Sciences Research Council

7

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A de novo designed hexameric coiled coil CC-Hex2 with farnesol bound in the channel.

2018
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Installing hydrolytic activity into a completely de novo protein framework.

2016 Nature Chemistry
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Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery.

2015 Journal of Medicinal Chemistry
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A Set of de Novo Designed Parallel Heterodimeric Coiled Coils with Quantified Dissociation Constants in the Micromolar to Sub-nanomolar Regime

2013 Journal of the American Chemical Society
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Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly

2013 Journal of the American Chemical Society
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