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Christopher A. Reynolds

University of Essex

160

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3683

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Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation

2021 bioRxiv
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Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

2021 bioRxiv
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Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

2021 bioRxiv
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Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins

2020
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A Multisite Model of Allosterism for the Adenosine A1 Receptor

2020 bioRxiv
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Non-opioid analgesia based on Gα signalling bias

2020 bioRxiv
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A biased adenosine A1R agonist confers analgesia without cardiorespiratory depression

2020 bioRxiv
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A Supervised Molecular Dynamics Approach to Unbiased Ligand–Protein Unbinding

2020 Journal of Chemical Information and Modeling
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Addressing free fatty acid receptor 1 (FFAR1) activation using supervised molecular dynamics.

2020 Journal of Computer-aided Molecular Design
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Activation of the GLP-1 receptor by a non-peptidic agonist

2020 Nature
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Citations (70)