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Virginia A. Zakian

Princeton University
Fred Hutchinson Cancer Research Center

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Pif1 family DNA helicases: a helpmate to RNase H?

2019 DNA Repair
- Thomas J. Pohl
- Virginia A. Zakian
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Saccharomyces cerevisiae Centromere RNA Is Negatively Regulated by Cbf1 and Its Unscheduled Synthesis Impacts CenH3 Binding

2019 Genetics
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Two Pif1-family DNA Helicases Cooperate in Centromere Replication and Segregation in Saccharomyces cerevisiae

2019 Genetics
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The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity

2018 Nucleic Acids Research
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Lack of positional requirements for autonomously replicating sequence elements on artificial yeast chromosomes (telomere replication/chromosome maintenance)

2016
- Raymund J. Wellinger
- Virginia A. Zakian
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Telomerase RNA is more than a DNA template

2016 RNA Biology
- Christopher J. Webb
- Virginia A. Zakian
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Getting it done at the ends: Pif1 family DNA helicases and telomeres

2016 DNA Repair
- Carly L. Geronimo
- Virginia A. Zakian
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Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity

2016 PLOS Genetics
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The Pif1 Helicase, a Negative Regulator of Telomerase, Acts Preferentially at Long Telomeres

2015 PLOS Genetics
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Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length

2015 Nature Communications
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