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Michelle D. Wahlin
Michelle D. Wahlin
University of Washington
Biochemistry
Lapatinib
Chemistry
CYP3A4
Glutathione
4
Papers
186
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Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib
2016
Drug Metabolism and Disposition
Joanna K Towles
Rebecca N Clark
Michelle D. Wahlin
Vinita Uttamsingh
Allan E. Rettie
Klarissa Hardy Jackson
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Citations (29)
Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG Cells
2013
Drug Metabolism and Disposition
Klarissa D. Hardy
Michelle D. Wahlin
Ioannis Papageorgiou
Jashvant D. Unadkat
Allan E. Rettie
Sidney D. Nelson
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Citations (29)
Metabolic Intermediate Complex Formation of Human Cytochrome P450 3A4 by Lapatinib
2011
Drug Metabolism and Disposition
Hideo Takakusa
Michelle D. Wahlin
Chunsheng Zhao
Kelsey L. Hanson
Lee Sun New
Eric Chun Yong Chan
Sidney D. Nelson
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Citations (43)
Mechanism-Based Inactivation of Cytochrome P450 3A4 by Lapatinib
2010
Molecular Pharmacology
Woon Chien Teng
Jing Wen Oh
Lee Sun New
Michelle D. Wahlin
Sidney D. Nelson
Han Kiat Ho
Eric Chun Yong Chan
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Citations (85)
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