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Kai Uwe Chow

Goethe University Frankfurt

33

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A Prospective, Open-Label, Multicenter, Phase 2 Trial to Evaluate the Safety and Efficacy of the Combination of Tirabrutinib (ONO/GS-4059) and Entospletinib with and without Obinutuzumab in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

2019 Blood
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Cytotoxic effects of the trifunctional bispecific antibody FBTA05 in ex-vivo cells of chronic lymphocytic leukaemia depend on immune-mediated mechanism

2011 Anti-Cancer Drugs
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Clinical efficacy of immunochemotherapy with fludarabine, epirubicin and rituximab in the treatment for chronic lymphocytic leukaemia and prolymphocytic leukaemia

2011 European Journal of Haematology
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Immunochemotherapy with rituximab in combination with fludarabine and epirubicine as first-line treatment in patients with chronic lymphocytic leukemia.

2010 Journal of Clinical Oncology
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Src kinase inhibitors induce apoptosis and mediate cell cycle arrest in lymphoma cells.

2007 Anti-Cancer Drugs
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The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines

2007 Leukemia & Lymphoma
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Novel Agents Aiming at Specific Molecular Targets Increase Chemosensitivity and Overcome Chemoresistance in Hematopoietic Malignancies

2006 Current Pharmaceutical Design
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Prostate-Apoptosis-Response-Gene-4: Biological Properties and their Potential Therapeutic Exploitation in Hematological Malignancies

2005 Letters in Drug Design & Discovery
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Imatinib induces apoptosis in CLL lymphocytes with high expression of Par-4.

2005 Leukemia
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Daxx overexpression in T-lymphoblastic Jurkat cells enhances caspase-dependent death receptor- and drug-induced apoptosis in distinct ways

2005 Cellular Signalling
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