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K. Narasimha Rao

Bhabha Atomic Research Centre

10

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Inhibition of dihydrofolate reductase and cell growth activity by the phenanthroindolizidine alkaloids pergularinine and tylophorinidine: the in vitro cytotoxicity of these plant alkaloids and their potential as antimicrobial and anticancer agents.

2000 Toxicology in Vitro
- K. Narasimha Rao
- S. R. Venkatachalam
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beta-Carboline-benzoquinolizidine alkaloid deoxytubulosine inhibits thymidylate synthase activity in leukemic leukocytes from patients with chronic myeloblastic leukemia and acute lymphoblastic leukemia.

1998 Anti-Cancer Drugs
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Thymidylate synthase activity in leukocytes from patients with chronic myelocytic leukemia and acute lymphocytic leukemia and its inhibition by phenanthroindolizidine alkaloids pergularinine and tylophorinidine

1998 Cancer Letters
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Inhibition of thymidylate synthase and cell growth by the phenanthroindolizidine alkaloids pergularinine and tylophorinidine

1997 Chemico-Biological Interactions
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Urinary 6‐hydroxymethylpterin levels accurately monitor response to chemotherapy in acute lymphoblastic leukemia

1982 Cancer
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Elevated urinary levels of 6‐hydroxymethylpterin during malignancy and liver regeneration: A simple, noninvasive test for cancer detection

1981 Cancer
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A general method for characterizing naturally occurring folate compounds, illustrated by characterizing Torula yeast (Candida utilis) folates☆

1978 Analytical Biochemistry
- K. Narasimha Rao
- J. M. Noronha
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Studies on the enzymatic hydrolysis of polyglutamyl folates by chicken liver folyl poly-γ-glutamyl carboxypeptidase II. Structural studies

1977 Biochimica et Biophysica Acta
- K. Narasimha Rao
- J. M. Noronha
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Studies on the enzymatic hydrolysis of polyglutamyl folates by chicken liver folyl poly-γ-glutamyl carboxypeptidase I. Intracellular localization, purification and partial characterization of the enzyme

1977 Biochimica et Biophysica Acta
- K. Narasimha Rao
- J. M. Noronha
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Citations (23)